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Cryptococcal Ag, Blood

Last modified by  gloria_crawford  on  April 03, 2014 09:58 AM

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514


Tube Type
gold top tube
Test ID   CRYS
EPIC Order
CPT Code(s)   86403, (86406 if positive)
Group/Individual Test   Individual
Laboratory   Clinical Immunology (Day Shift, M-F)
Clinical Microbiology (Weekends, Evenings, Nights)
Tube Station   30 (Routine)
82 (STAT)
Specimen Routine: 2 ml blood/Serum Separator Tube/Gold Top
Availability Routine: Monday-Friday
  STAT: YES (24 Hours/7 Days/Week)
Turnaround Time   2 hours (STAT); 1-3 days(Routine)
Reference Range Normal: Negative

Serum samples submitted for cryptococcal antigen testing are incubated with latex particles coated with murine IgM monoclonal antibodies to the cryptococcal capsular polysaccharide antigen (CPS).  Results are reported as negative or positive.  Positive results are accompanied by the endpoint titer determined by serial dilution of the patient’s serum.  False positive results have been documented with the polysaccharide antigen of Trichosporon beigelii.



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